Phosphatidylserine
A phospholipid found in neuronal cell membranes, relevant to mental clarity.
| Category | Phospholipid |
|---|---|
| Amount per capsule | Not disclosed — see label |
| Evidence strength | Modest support |
What it is
Phosphatidylserine is a phospholipid — a type of fat molecule that's a structural component of every cell membrane in the body, including neuronal cell membranes in the brain.
How it's associated with cognition
Because it's a building block of the membranes that neurons use to communicate with each other, phosphatidylserine is studied for its role in supporting cell membrane fluidity — relevant to how efficiently neurons signal and, by extension, to mental clarity.
What the evidence actually shows
Research on phosphatidylserine for age-related memory is modest rather than strong. It's one of the more mechanistically well-understood ingredients in the formula, but the effect size in human trials tends to be smaller than for Bacopa or Ginkgo.
Why it's in the formula
Phosphatidylserine addresses cell membrane structure specifically — a different target than circulation (Ginkgo) or neurotransmitter pathways (Bacopa), rounding out the formula's mechanistic coverage.
Safety notes
Phosphatidylserine is generally well tolerated at supplement-level doses. As with any supplement, check with a doctor first if you're pregnant, nursing, or taking medication.